SeedHorse Chestnut
Moderate evidence supports horse chestnut seed extract for short-term relief of chronic venous insufficiency symptoms, with limited evidence for other traditional uses.
Benefits
- Anti-inflammatory
- venotonic
- vascular protective
- anti-edematous
- improves blood vessel tone
- neuroprotective
- antitumor effects.
Key compounds
Aescin (escin)aesculetintriterpenoid saponins
May help with
- Traditionally used for arthritis
- pain
- swelling
- menstrual cramps
- hemorrhoids
- and promoted for chronic venous insufficiency
- irritable bowel syndrome
- and male infertility.
Best for these goals
Anti-inflammatoryvenotonicvascular protectiveanti-edematousimproves blood vessel toneneuroprotectiveantitumor effects.
How to use it
Standardized seed extracts, oral supplements
Evidence level
Moderate
Cautions & interactions
Raw seeds, bark, flowers, and leaves are toxic; standardized extracts are generally safe for short-term use (up to 12 weeks); side effects include dizziness, digestive upsets, headache, itching; contraindicated in pregnancy, breastfeeding, and those with kidney or liver impairment. | Interactions: May increase bleeding risk with anticoagulants (warfarin, aspirin) or antiplatelet drugs; may interact with CYP450 substrate drugs; use with caution.
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