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Herb

Butterbur

Moderate evidence supports PA-free butterbur for migraine prevention and allergic rhinitis; limited evidence for asthma. Concerns exist regarding pyrrolizidine alkaloids.

Benefits

Key compounds

Petasinsisopetasinneopetasinquercetin glucosidescaffeic aciddicaffeoylquinic acidsisoquercitrinastralagin

May help with

Best for these goals

May help prevent migraines and alleviate symptoms of allergic rhinitis and asthmaexhibits anti-inflammatoryantioxidantand potential antiviral properties.

How to use it

PA-free extracts, capsules

Evidence level

Moderate

Cautions & interactions

Contains hepatotoxic pyrrolizidine alkaloids (PAs); only use certified PA-free products. May cause liver injury, belching, diarrhea, drowsiness, rash, stomach upset, or allergic reactions in sensitive individuals. Avoid during pregnancy/lactation and in liver disease. | Interactions: No major interactions documented; use standard caution. Consult healthcare provider if taking any medications.
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Educational information only — not medical advice, and not evaluated by the FDA. These statements are not intended to diagnose, treat, cure, or prevent any disease. Talk to a qualified healthcare provider before using any ingredient therapeutically, especially if pregnant, nursing, or taking medication.

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