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Herb

Jamaican Dogwood

Limited human scientific evidence supports traditional uses; animal studies suggest sedative, anxiolytic, antispasmodic, anti-inflammatory, and hypotensive activities, but significant safety concerns exist.

Benefits

Key compounds

PiscidinJamaicineRotenoneIchthynoneMillettoneSumatrolDurmilloneErythynoneIsoflavonoidsPyrano-rotenoids

Best for these goals

Traditionally recognized for calming the nervous systemeasing tensionand providing minor pain reliefalso noted for muscle-relaxant and hypotensive effects.

How to use it

Tinctures, decoctions (bark tea), powdered bark

Evidence level

Safety concern

Cautions & interactions

Likely unsafe when taken by mouth due to toxicity; side effects include numbness, tremors, salivation, and sweating. Avoid during pregnancy, breastfeeding, in children, and at least 2 weeks before surgery. | Interactions: May have moderate interaction with sedative medications (CNS depressants), potentially causing increased sleepiness and slowed breathing.
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Educational information only — not medical advice, and not evaluated by the FDA. These statements are not intended to diagnose, treat, cure, or prevent any disease. Talk to a qualified healthcare provider before using any ingredient therapeutically, especially if pregnant, nursing, or taking medication.

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