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Herb

Oregon Grape

Limited evidence suggests topical Oregon grape cream may improve psoriasis symptoms; insufficient evidence for other conditions.

Benefits

Key compounds

berberineberbaminecanadinehydrastine

May help with

Best for these goals

May help fight bacterial and fungal infectionsmay reduce inflammationimmune supportivestimulates digestionrelieves intestinal spasms.

How to use it

topical cream, tea, tincture

Evidence level

Limited

Cautions & interactions

Likely unsafe during pregnancy and breastfeeding due to berberine; likely unsafe for newborns due to jaundice risk; may cause itching, burning, irritation, allergic reactions topically. | Interactions: Interacts with medications moved by cellular pumps, cyclosporine, liver-metabolized drugs (CYP3A4, CYP2C9, CYP2D6), diabetes drugs, blood pressure drugs, blood thinners, sedatives, and tetracycline.
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Educational information only — not medical advice, and not evaluated by the FDA. These statements are not intended to diagnose, treat, cure, or prevent any disease. Talk to a qualified healthcare provider before using any ingredient therapeutically, especially if pregnant, nursing, or taking medication.

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