HerbPassionflower
Small human studies suggest passionflower may reduce anxiety and improve sleep, but long-term safety and efficacy are not definitively established for these or other conditions.
Benefits
- Traditionally used as a sedative
- promoted for calming
- anxiety reduction
- and sleep support
- animal studies suggest mild anti-inflammatory and anti-seizure activity.
Key compounds
Harmanharmalinemaltolgamma-pyrone derivativeschrysin
May help with
- Historically used as a sedative in European folk medicine
- traditional uses include insomnia
- anxiety
- epilepsy
- neuralgia
- and withdrawal symptoms.
Best for these goals
Traditionally used as a sedativepromoted for calminganxiety reductionand sleep supportanimal studies suggest mild anti-inflammatory and anti-seizure activity.
How to use it
Tea, extract
Evidence level
Limited
Cautions & interactions
Possible side effects include drowsiness, dizziness, confusion; avoid during pregnancy due to potential uterine contractions; caution before surgery; large doses may cause CNS depression and irregular heart rhythms. | Interactions: May increase sedative effects of anesthesia, benzodiazepines, and other sleep aids; potential additive effects with St. John's Wort, valerian, and drugs that prolong QT interval; caution with CYP3A4 substrates.
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